FUNCTIONALIZED NANOPARTICLES FOR BIOMEDICAL APPLICATIONS
We deal with the synthesis of tailored-functionalized nanoparticles for distinct biomedical applications. Usually, these nanoparticles are precisely designed in order to answer specific questions related to bionanointerface. Currently, we are focused on distinct systems which are mainly applied for preventing bacterial replication, killing tumor cells and avoiding viral infection.
AGGREGATION OF NANOPARTICLES IN BIOLOGICAL FLUIDS
The use of nanoparticles as commercial drugs depends on the stability of the entire system when in presence of complex biological fluids. We are working towards to understand these effects that promote nanoparticles' aggregation in physiological media. Several nanoparticles have been designed to address fundamental aspects of aggregation in biological media.
LOCALIZATION OF NANOPARTICLES INTO MICROORGANISMS
A challenging task for the ample nanotechnology development is related to the location of nanoparticles into microorganisms. This is a long-term question that has been discussed for many years and, particularly, we are trying to get answers based on X-ray and confocal microscopies as well as coherent diffraction imaging in order to image nanoparticles inside cells, bacteria and viruses.
NANOPARTICLES AS SENSORS
Sensing area is based on our previous knowledge on the design of multifunctional nanoparticles which can be used for a broad range of different analytes. We are particularly interested in nanoparticles processes that use differential binding through pattern recognition technique. Our interest is currently focused on selectivity rather than specificity.